有紅斑性狼瘡和氣喘患者,隔一個月再確診,連看了3次門診都拿不到口服藥,症狀還是嚴重,跑第四家醫院醫師評估狀況根本得收治住院,才開出抗病毒藥,讓患者一波三折,其他醫師說可能診所擔心交互作用,不敢隨意給藥,否則有自體免疫疾病患者,要防止中重症都能直接給抗病毒藥。
Airway smooth muscle (ASM)
氣道平滑肌 (ASM)
The excessive contractile response of ASM in asthma results in inordinate bronchoconstriction and airflow obstruction in response to relatively little provocation
ASM 在哮喘中的過度收縮反應導致支氣管過度收縮和氣流阻塞
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Bronchial smooth muscle contraction induces airway narrowing.
支氣管平滑肌收縮導致氣道變窄。
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Ultimately, asthma is a disease characterized by constriction of airway smooth muscle (ASM).
歸根結底,哮喘是一種以氣道平滑肌 (ASM) 收縮為特徵的疾病。
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Airway smooth muscle (ASM)
氣道平滑肌 (ASM)
ASM contraction and relaxation are dependent on changes in cytosolic and mitochondrial calcium.
ASM 的收縮和鬆弛取決於細胞溶質和線粒體鈣的變化。
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A primary mechanism common to all of the neurotransmitters and physical factors that elicits smooth muscle contraction in variant angina or asthma is an increased free calcium in the cytoplasm. Thus, all muscle contracts and relaxes in association with increases and decreases of intracellular free calcium.
在變異型心絞痛或哮喘中引起平滑肌收縮的所有神經遞質和物理因素的共同主要機制是細胞質中游離鈣的增加。 因此,所有肌肉都隨著細胞內游離鈣的增加和減少而收縮和放鬆。
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Contractility of airway smooth muscle requires elevation of intracellular calcium concentration.
氣道平滑肌的收縮性需要細胞內鈣濃度的升高。